Coagulation disorders and the IPF puzzle

Coagulation disorders and the IPF puzzle.

While idiopathic pulmonary fibrosis (IPF) remains a frustrating mystery for patients and their physicians, growing evidence from a number of different sources provides potentially clinically relevant clues to the puzzle of this largely untreatable and highly fatal disorder. 2 Answers to frequently asked questions from patients of ‘why me?’ ‘what is the cause?’ ‘what can be done?’ and ‘what can ...

The Rare Coagulation Disorders

Disseminated intravascular coagulation and coagulation disorders.

PURPOSE OF REVIEW An update on recent developments in diagnosis and treatment of disseminated intravascular coagulation. RECENT FINDINGS Disseminated intravascular coagulation is defined as a typical disease condition with laboratory findings indicating massive coagulation activation and reduction in procoagulant capacity. Clinical syndromes associated with the condition are consumption coagu...

Coagulation and Mental Disorders

The neurovascular unit is a key player in brain development, homeostasis, and pathology. Mental stress affects coagulation, while severe mental illnesses, such as recurrent depression and schizophrenia, are associated with an increased thrombotic risk and cardiovascular morbidity. Evidence indicates that the hemostatic system is involved to some extent in the pathogenesis, morbidity, and progno...

Coagulation disorders.

The risk of severe haemorrhage in pregnancy is well recognized, and uncontrolled bleeding remains a major cause of maternal death throughout the world, including the British Isles. The haemochorial system of human placentation carries with it an inherent risk of haemorrhage and this probably explains why the serious congenital disorders of haemostasis are predominantly found in the male. In pre...